Clomox

Injection Clomox contains Amoxicillin + Cloxacillin Injection is a broad‑spectrum antibacterial combination formulated for the management of acute and severe bacterial infections. This combination provides dual action against a wide range of Gram‑positive and select Gram‑negative organisms, making it particularly effective where mixed infections are suspected or confirmed.
Key Features:
Broad-spectrum activity: Effective against β‑lactamase–producing and non‑producing bacteria.
Bactericidal action: Both components belong to the penicillin class and work synergistically to inhibit bacterial cell‑wall synthesis.
Rapid therapeutic response: Suitable for serious infections requiring immediate high plasma concentrations.
Mechanism of Action:
Amoxicillin Sodium
A semi‑synthetic aminopenicillin effective against many Gram‑positive and Gram‑negative bacteria. It interferes with cell‑wall synthesis during bacterial replication, leading to cell lysis.
Cloxacillin Sodium
A β‑lactamase‑resistant penicillin effective primarily against Gram‑positive bacteria, including penicillinase‑producing staphylococci. It protects the formulation from enzymatic degradation, ensuring improved antibacterial efficacy.

Each vial contains꞉
Amoxycillin Sodium IP 2.25 gm
Cloxacillin Sodium IP 2.25 gm

This combination is typically recommended for:

1. Severe skin and soft tissue infections
2. Lower and upper respiratory tract infections
3. ENT infections
4. Osteomyelitis
5. Post‑operative wound infections
6. Other infections where β‑lactamase–producing organisms are suspected

1 vial daily by IM/IV route