Tinacef

Injection Tinacef contains Ceftriaxone and Sulbactam used for mastitis, This product is a broad‑spectrum, third‑generation cephalosporin antibiotic (Ceftriaxone) combined with the β‑lactamase inhibitor Sulbactam, formulated to provide enhanced and reliable coverage against a wide range of bacterial pathogens. The addition of Sulbactam protects Ceftriaxone from enzymatic degradation by β‑lactamase–producing organisms, thereby restoring and significantly enhancing its antibacterial activity.
Key Features & Benefits
Broad-spectrum antibacterial coverage against Gram‑positive, Gram‑negative, and anaerobic pathogens.
Highly effective in treating mastitis, metritis, pneumonia, urinary tract infections (UTI), soft‑tissue infections, and infections involving the central nervous system (CSF).
Sulbactam improves the efficacy of Ceftriaxone against organisms that exhibit resistance due to β‑lactamase production.
Suitable for severe, mixed, and complicated infections where a potent, combination therapy is required.
Offers strong tissue penetration, making it effective in deep and difficult‑to‑reach infection sites.
Mechanism of Action:
Ceftriaxone inhibits bacterial cell‑wall synthesis by binding to penicillin‑binding proteins (PBPs), leading to cell lysis and death.
Sulbactam irreversibly inhibits β‑lactamase enzymes produced by resistant bacteria, preventing Ceftriaxone degradation and extending its antimicrobial spectrum.
Together, they provide a synergistic effect, making the formulation particularly useful in infections caused by penicillin‑resistant and β‑lactamase–producing strains. Metritis, pneumonia, UTI, soft tissue and CSF infections.
Effective against penicillin‑resistant bacteria due to β‑lactamase inhibition.

Each 3 gm vial contains꞉ Ceftriaxone Sodium IP (Sterile) equivalent to Ceftriaxone. 2000 mg
Sulbactam Sodium IP (Sterile) equivalent to Sulbactam. 1000 mg; Each 4.5 gm vial contains꞉ Ceftriaxone Sodium IP (Sterile) equivalent to Ceftriaxone. 3000 mg
Sulbactam Sodium IP (Sterile) equivalent to Sulbactam. 1500 mg

• Mastitis
• Metritis
• Urinary tract infections
• Other soft tissue infections
• Pneumonia
• CSF infections

1 Vial I/V or I/M daily for 3 days